Welcome to India's first Website with complete information on Infectious deseases, Vaccines, Immunisation and Immunoglobulins. + + + Become a registered member of the site and recieve latest balanced information from the world of Vaccines.

SAFETY

Rating for vaccineindia.org

Poll Manager

How Many Vaccination Centres maintain cold chain strictly?
 

Who's Online

We have 74770 guests online

Statistics

Members : 1154
Content : 369
Web Links : 19
Content View Hits : 10787068
PDF Print E-mail

ROTA VIRUS DISEASE

 

Rota virus is the most common cause of severe diarrhea in infants and children

Responsible for 27,000 diarrheal deaths each year worldwide

Symptoms

  • Incubation period 1 – 3 days
  • Acute watery diarrhea – self-limiting, usually 2 – 7 days, possibly longer
  • Fever - first few days - can be high
  • Vomiting - first few days
  • G1 symptoms may last upto 2 – 3 weeks

             

Compared to other common causes of diarrhea – more severe with greater risk of dehydration & hospitalization

 

Rotavirus Strains

  • 7 different serogroups (A-G)
  • Only A-C cause human disease
  • Only A cause severe disease in children
  • Serotyping based on 2

            structural proteins (GVP7 & PVP4)

            – 11 possible “G” serotypes (1, 2, 3, 4, 9)

            – 11 possible “P” serotypes (4, 8)

  • Strains vary: By region and Over time
  • 5 serotypes (G1P8, G2P4, G3P8, G4P8, G9P8) cause 90% of all human infections.
  • G1P8 most prevalent globally.
  • No relation between strain and severity

 

Deaths due to rotavirus annually *

India : 122,270  World : 527,000 (4,75,000 – 5,80,000)

  • 29% of all deaths due to diarrhea globally.
  • 20% of all deaths in children <5 years of age from India are due to diarrhea.
  • 39.2% of all diarrhea-related hospital admissions among children aged <5 years in India (range from 35% in Mumbai to 53% in Trichy).
  • 23% of deaths due to rotavirus in world.

OPD visits >25 million

Hospitalization >2 million

*Umesh Parashar, et al Global Mortality Associated with Rotavirus among Children

 

Reinfection is common but symptoms will be less significant.

Transmission is Feco-oral, person-person, fomites. Clean water, hygiene unlikely to have substantial effect on virus transmission.

  • First infection usually does not lead to permanent immunity
  • Reinfection can occur at any age
  • Subsequent infections generally less severe

 

Most Common Types of Rotavirus Strains Found by the IRSN

G1 P[8]

22.10%

G2 P[4]

25.70%

G9 P[8]

8.50%

G12 P[4] 6[][8]

6.50%

 

International authorities (WHO, Institutes for Medicine, GAVI) highlight need for rotavirus vaccines

  • Disease not prevented by good sanitation & hygiene
  • Despite potential for ORS, IV fluids often needed for severe disease

Glass R et al. Lancet 2006;368:323-332

 

 

Comments   

 
Amber Volkart
0 # age group of rota virusAmber Volkart 2011-09-10 14:39
Dear,
plea se inform the age-group of rota virus infection...

than ks and regards,
ambe r
Reply | Reply with quote | Quote
 
 
canavanqwc
+1 # Continued on the shoulders of giants, ascendancy is relatively uncomplicatedcanavanqwc 2012-05-18 19:21
You are an pundit on this, please [url=[censored] :[censored][cen sored]www.cinae scort.com[censo red]shenzhen-es cort.html]shenz hen massage[[censor ed]url] avoid us to explain.
Reply | Reply with quote | Quote
 
 
dr.g.a.manjunath
+1 # latest straindr.g.a.manjunath 2013-06-09 21:11
Can u plz inform me the latest strain prevailing in india ?
Reply | Reply with quote | Quote
 
 
ATUL SOPAN BHUJBAL
-1 # queryATUL SOPAN BHUJBAL 2014-07-04 22:37
please i infromation rota virus my son is 7 months complete hense canfuse rota virus medicine not given to help me?
Reply | Reply with quote | Quote
 
 
Rory
0 # ROTA VIRUS DISEASERory 2014-07-07 22:16
Its such as you learn my mind! You appear to
know a lot approximately this, such as you wrote the guide in it or something.

I believe that you could do with a few % to force the message house a little bit, however instead
of that, that is wonderful blog. An excellent read. I will definitely be back.


Here is my web blog - lancaster cattery: [censored]s:[ce nsored][censore d]plus.google.c om[censored]+Gr eenbankBoarding KennelsandCatte ryWarton[censor ed]about
Reply | Reply with quote | Quote
 
 
Katharina
0 # ROTA VIRUS DISEASEKatharina 2014-07-28 06:00
For the latest information on the HP computer Roll Off Dumpster programs, some even pay you money, as you will
soon see. To create recycled cardboard crafts, you
will save a lot of enemies.

Also visit my web page rental search: [censored]:[cen sored][censored ]sportsfan.me[c ensored]reliabl edumpsters
Reply | Reply with quote | Quote
 
 
Blair
0 # ROTA VIRUS DISEASEBlair 2014-09-15 08:23
When starting a school Roll Off Container program for two reasons.
Rag rugs are a traditional and somewhat classic hand woven craft, and
as long as they are often not intended to be sold in bulk to junk houses for a good
caus e. This resulted in a much more complex matter
and, consequently, despite being a high value resource, only
abou t 5% of plastics can be recovered and recycled. This will occupy space in the house.
They come in a wide variety of new products.

my blog post; dumpster rental ma: [censored]:[cen sored][censored ]www.reliabledu mpsterrentals.c om[censored]cal ifornia[censore d]dumpster-rent al-grover-beach -ca[censored]
Reply | Reply with quote | Quote
 
 
shakeel
0 # rotavirus how many months to provide childshakeel 2015-04-22 20:12
Please inform age groups of rotavirus infection how many times provide children my child 5months old
Reply | Reply with quote | Quote
 

Add comment


Security code
Refresh