Welcome to India's first Website with complete information on Infectious deseases, Vaccines, Immunisation and Immunoglobulins. + + + Become a registered member of the site and recieve latest balanced information from the world of Vaccines.
PDF Print E-mail

ROTA VIRUS DISEASE

 

Rota virus is the most common cause of severe diarrhea in infants and children

Responsible for 27,000 diarrheal deaths each year worldwide

Symptoms

  • Incubation period 1 – 3 days
  • Acute watery diarrhea – self-limiting, usually 2 – 7 days, possibly longer
  • Fever - first few days - can be high
  • Vomiting - first few days
  • G1 symptoms may last upto 2 – 3 weeks

             

Compared to other common causes of diarrhea – more severe with greater risk of dehydration & hospitalization

 

Rotavirus Strains

  • 7 different serogroups (A-G)
  • Only A-C cause human disease
  • Only A cause severe disease in children
  • Serotyping based on 2

            structural proteins (GVP7 & PVP4)

            – 11 possible “G” serotypes (1, 2, 3, 4, 9)

            – 11 possible “P” serotypes (4, 8)

  • Strains vary: By region and Over time
  • 5 serotypes (G1P8, G2P4, G3P8, G4P8, G9P8) cause 90% of all human infections.
  • G1P8 most prevalent globally.
  • No relation between strain and severity

 

Deaths due to rotavirus annually *

India : 122,270  World : 527,000 (4,75,000 – 5,80,000)

  • 29% of all deaths due to diarrhea globally.
  • 20% of all deaths in children <5 years of age from India are due to diarrhea.
  • 39.2% of all diarrhea-related hospital admissions among children aged <5 years in India (range from 35% in Mumbai to 53% in Trichy).
  • 23% of deaths due to rotavirus in world.

OPD visits >25 million

Hospitalization >2 million

*Umesh Parashar, et al Global Mortality Associated with Rotavirus among Children

 

Reinfection is common but symptoms will be less significant.

Transmission is Feco-oral, person-person, fomites. Clean water, hygiene unlikely to have substantial effect on virus transmission.

  • First infection usually does not lead to permanent immunity
  • Reinfection can occur at any age
  • Subsequent infections generally less severe

 

Most Common Types of Rotavirus Strains Found by the IRSN

G1 P[8]

22.10%

G2 P[4]

25.70%

G9 P[8]

8.50%

G12 P[4] 6[][8]

6.50%

 

International authorities (WHO, Institutes for Medicine, GAVI) highlight need for rotavirus vaccines

  • Disease not prevented by good sanitation & hygiene
  • Despite potential for ORS, IV fluids often needed for severe disease

Glass R et al. Lancet 2006;368:323-332

 

 

Comments   

 
Amber Volkart
0 # age group of rota virusAmber Volkart 2011-09-10 14:39
Dear,
plea se inform the age-group of rota virus infection...

than ks and regards,
ambe r
Reply | Reply with quote | Quote
 
 
canavanqwc
+1 # Continued on the shoulders of giants, ascendancy is relatively uncomplicatedcanavanqwc 2012-05-18 19:21
You are an pundit on this, please [url=[censored] :[censored][cen sored]www.cinae scort.com[censo red]shenzhen-es cort.html]shenz hen massage[[censor ed]url] avoid us to explain.
Reply | Reply with quote | Quote
 
 
dr.g.a.manjunath
+1 # latest straindr.g.a.manjunath 2013-06-09 21:11
Can u plz inform me the latest strain prevailing in india ?
Reply | Reply with quote | Quote
 
 
ATUL SOPAN BHUJBAL
-1 # queryATUL SOPAN BHUJBAL 2014-07-04 22:37
please i infromation rota virus my son is 7 months complete hense canfuse rota virus medicine not given to help me?
Reply | Reply with quote | Quote
 
 
Rory
0 # ROTA VIRUS DISEASERory 2014-07-07 22:16
Its such as you learn my mind! You appear to
know a lot approximately this, such as you wrote the guide in it or something.

I believe that you could do with a few % to force the message house a little bit, however instead
of that, that is wonderful blog. An excellent read. I will definitely be back.


Here is my web blog - lancaster cattery: [censored]s:[ce nsored][censore d]plus.google.c om[censored]+Gr eenbankBoarding KennelsandCatte ryWarton[censor ed]about
Reply | Reply with quote | Quote
 
 
Katharina
0 # ROTA VIRUS DISEASEKatharina 2014-07-28 06:00
For the latest information on the HP computer Roll Off Dumpster programs, some even pay you money, as you will
soon see. To create recycled cardboard crafts, you
will save a lot of enemies.

Also visit my web page rental search: [censored]:[cen sored][censored ]sportsfan.me[c ensored]reliabl edumpsters
Reply | Reply with quote | Quote
 
 
Blair
0 # ROTA VIRUS DISEASEBlair 2014-09-15 08:23
When starting a school Roll Off Container program for two reasons.
Rag rugs are a traditional and somewhat classic hand woven craft, and
as long as they are often not intended to be sold in bulk to junk houses for a good
caus e. This resulted in a much more complex matter
and, consequently, despite being a high value resource, only
abou t 5% of plastics can be recovered and recycled. This will occupy space in the house.
They come in a wide variety of new products.

my blog post; dumpster rental ma: [censored]:[cen sored][censored ]www.reliabledu mpsterrentals.c om[censored]cal ifornia[censore d]dumpster-rent al-grover-beach -ca[censored]
Reply | Reply with quote | Quote
 
 
shakeel
0 # rotavirus how many months to provide childshakeel 2015-04-22 20:12
Please inform age groups of rotavirus infection how many times provide children my child 5months old
Reply | Reply with quote | Quote
 

Add comment


Security code
Refresh